No, just look at their “About Me” and link settings as a new user. If they don’t look spammy, then you are fine.
But it is a hallmark of spammers to sign up, read nothing, and fill these fields with spam. It has no real effect since we don’t show links of any kind on TL0 user profiles; try viewing a TL0 user profile as an anonymous / incognito user to see what I mean.