Chrome: ERR_SSL_PROTOCOL_ERROR, FF: SSL_ERROR_RX_RECORD_TOO_LONG for a few users on established forum

Is it a standard install or do you have a reverse proxy in front?

What’s the url so we can look at the certificate?

What is the the logs (/var/discourse/shared/standalone/logs/rails/production.log and the nginx log, which you’ll have to search for)

Did you do a rebuild or upgrade from the web interface? You should do a rebuild.