This is probably best presented as a feature request, something along the line of an option to “Replace confusable unicode characters before applying Watched Words”.
# C Ⅽ C ௐ С Ꮯ Ⲥ ꓚ Ϲ ℂ ℭ 𝐂 𝐶 𝑪 𝒞 𝓒 𝕮 𝖢 𝗖 𝘊 𝘾 𝙲
( C ) 0043 LATIN CAPITAL LETTER C
← ( Ⅽ ) 216D ROMAN NUMERAL ONE HUNDRED
← ( C ) FF23 FULLWIDTH LATIN CAPITAL LETTER C # →С→
← ( ௐ ) 0BD0 TAMIL OM # →С→
← ( С ) 0421 CYRILLIC CAPITAL LETTER ES
← ( Ꮯ ) 13DF CHEROKEE LETTER TLI
← ( Ⲥ ) 2CA4 COPTIC CAPITAL LETTER SIMA # →Ϲ→
← ( ꓚ ) A4DA LISU LETTER CA
← ( Ϲ ) 03F9 GREEK CAPITAL LUNATE SIGMA SYMBOL
← ( ℂ ) 2102 DOUBLE-STRUCK CAPITAL C
← ( ℭ ) 212D BLACK-LETTER CAPITAL C
← ( 𝐂 ) 1D402 MATHEMATICAL BOLD CAPITAL C
← ( 𝐶 ) 1D436 MATHEMATICAL ITALIC CAPITAL C
← ( 𝑪 ) 1D46A MATHEMATICAL BOLD ITALIC CAPITAL C
← ( 𝒞 ) 1D49E MATHEMATICAL SCRIPT CAPITAL C
← ( 𝓒 ) 1D4D2 MATHEMATICAL BOLD SCRIPT CAPITAL C
← ( 𝕮 ) 1D56E MATHEMATICAL BOLD FRAKTUR CAPITAL C
← ( 𝖢 ) 1D5A2 MATHEMATICAL SANS-SERIF CAPITAL C
← ( 𝗖 ) 1D5D6 MATHEMATICAL SANS-SERIF BOLD CAPITAL C
← ( 𝘊 ) 1D60A MATHEMATICAL SANS-SERIF ITALIC CAPITAL C
← ( 𝘾 ) 1D63E MATHEMATICAL SANS-SERIF BOLD ITALIC CAPITAL C
← ( 𝙲 ) 1D672 MATHEMATICAL MONOSPACE CAPITAL C
(hah, I just discovered that chromium implements this simplification, when attempting to search for 𝑪 it found most confusable instances of the letter C - try it here!)
An example algorithm using this data is implemented in python here.
In your last screenshot @billgraziano the first ampersand-encoded numeric character reference you post ( 𝐇 ) would be:
← ( 𝐇 ) 1D407 MATHEMATICAL BOLD CAPITAL H
(the ordinal for 𝐇 is 119815 encoded in decimal or 1D407 encoded in hex)
So a complete case-insensitive regex for “helpline” you could use would be: