One thing I’ve noticed is that the admin section warns that
The server is configured to upload files to S3, but there is no S3 CDN configured. This can lead to expensive S3 costs and slower site performance. See “Using Object Storage for Uploads” to learn more.
I don’t mind ignoring it, but we have secure media enabled which means it’s not possible to use a CDN. This message probably shouldn’t be shown on sites with secure_media enabled.