Make sure your EC2 instance has the right permissions to upload to S3, like s3:PutObject and s3:GetObject. Double-check your S3 bucket’s region and access settings. You might also want to try turning on s3_use_acls: true if necessary. You can also test uploading directly with AWS CLI to rule out permission issues. And if you’re not using direct uploads, just leave enable_direct_s3_uploads: f as is. Should help fix the problem!