We have Customize subject format for standard emails but this does not have anything to do with digest emails.
I don’t know about others, but I am finding that the digest email format is too rigid and makes for boring, too long subject lines. I want to have a very informative, long site title for the purposes of the welcome email and page titles, but then that makes for a cumbersome and long subject line for digest emails.
I also agree it would be very nice to be able to feature a top post title in the digest subject. This is especially valuable for small, not so buzzing communities when there’s often only one post in the digest (and it would help if it were possible to reply to it if that’s the case).